Hyperosmolar Hyperglycemic Non-Ketotic Coma

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Hyperosmolar non-ketotic diabetic coma and rhabdomyolysis.

Rhabdomyolysis is a rare but potentially fatal complication of hyperosmolar states. We report a case of severe hyperosmolar non-ketotic diabetic coma causing rhabdomyolysis in a young man. Despite very high levels of creatine kinase there was no detectable myoglobinuria. Creatine kinase estimation should be a standard investigation in all patients presenting with a hyperosmolar state.

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Hyperosmolar Hyperglycemic Non Ketotic Coma and Rhabdomyolysis; An Uncommon Clinical Encounter

Rhabdomyolysis is usually attributed to trauma. However there is an association of rhabdomyolysis with hyperosmolar states. Recognition of this association will enable better management of the patient and reduce the burden on the care taker by preventing the onset of complications that can prove fatal. It is also important to realise that hyperosmolar coma can be the presenting complaint of a d...

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Hyperosmolar hyperglycaemic non-ketotic diabetic coma complicating open heart surgery.

The syndrome of hyperosmolar hyperglycaemic non-ketotic diabetic coma was first described by Sament and Schwartz in 1957. In a recent publication, McCurdy (I970) reviewed the details of 84 cases. Various possible aetiological factors have been considered, and in an Editorial in journal of the American Medical Association (I968), attention was drawn to an iatrogenic element. It has complicated p...

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Hyperosmolar non-ketotic diabetes.

Hyperosmolar non-ketotic crises occur chiefly in mild, maturity-onset diabetics, yet present a medical emergency carrying a high mortality. This may in part be due to a lack of awareness of the clinical presentation, and of the principles of treatment. Five cases are described, in all of which excessive consumption of Lucozade, a proprietary 'glucose' drink, played an important part in the deve...

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The role of race and environment in the development of hyperosmolar hyperglycaemic non-ketotic coma.

Introduction It has been reported that hyperosmolar hyperglycaemic non-ketotic coma (HHNC) occurs more commonly in black patients (Pyke, 1969) and this has become an accepted part of clinical teaching on the subject (Oakley, Pyke and Taylor, 1978; Jackson and Vinik, 1977). Recently this point has been further emphasized (Nikolaides et al., 1981; Wright et al., 1981). Our personal observations h...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1968

ISSN: 0003-4932

DOI: 10.1097/00000658-196804000-00012